{"id":175,"date":"2023-04-04T14:40:53","date_gmt":"2023-04-04T12:40:53","guid":{"rendered":"https:\/\/neores.se\/?page_id=175"},"modified":"2026-01-05T21:29:00","modified_gmt":"2026-01-05T20:29:00","slug":"innovations","status":"publish","type":"page","link":"https:\/\/neores.se\/?page_id=175","title":{"rendered":"Innovations"},"content":{"rendered":"

Dynamics analysis neopuff and inspire rPAP by Berger et al.<\/h2>

\u2022 Inspire rPAP showed 6.3\u202f% pressure fluctuation vs. 46.1\u202f% for Neopuff.
\n\u2022 Device geometry drives pressure stability differences.
\n\u2022 Inspire rPAP\u2019s design lowers imposed work of breathing in neonates.
\n\u2022 Neopuff\u2019s T-piece caused vortices during exhalation.
\n\u2022 CFD modeling proved effective for optimizing neonatal CPAP performance.<\/p> Berger et al. Respiratory Physiology & Neurobiology 2026 <\/a> <\/div>

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<\/span><\/i><\/span><\/div>Inspiration Healthcare<\/a><\/div>\n
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rPAP<\/h2>\n

Worldwide around 15 million babies are born prematurely every year. The majority during gestational weeks 32\u201336 and they account for most of the mortality and neurological disability among preterm infants. Premature babies often need help with breathing. Traditional resuscitation devices for preterm infants have a high resistance to air flow that makes it difficult for the infant to breathe through. The rPAP is CE marked by Inspiration Healthcare.<\/p>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>

The driving force<\/h2>

rPAP use the same design as Infant Flow to generate CPAP and PEEP. This clever design use an ustable jet that supports inhalation  and has no resistance on exhalation. The research group invesigated this in a collaboration with KTH, Stockholm and prof. Lisa Prahl Wittberg.<\/p>KTH manuscript<\/a> Show CFD video<\/a><\/div>

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Nebulisation<\/h2>\n

For several years we worked with optimization and factors affecting delivery of aerosols and nebulised drugs during CPAP. The factors were examined by the research group and investigated using filter deposition of Tc-99m. We had acceptable deposition and was able to optimize delivery. There has been a decline in interest in surfactant even if other drugs could be of interest.<\/p>\n\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>

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Material published on Youtube on rPAP from Inspiration Healthcare<\/p>\n

Watch on Youtube <\/a><\/p>\n\n<\/div>\n

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Material published on Youtube on rPAP vs Neopuff from A Prost<\/p>\n

Watch on Youtube<\/a><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>

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Dynamics analysis neopuff and inspire rPAP by Berger et al. \u2022 Inspire rPAP showed 6.3\u202f% pressure fluctuation vs. 46.1\u202f% for Neopuff. \u2022 Device geometry drives pressure stability differences. \u2022 Inspire rPAP\u2019s design lowers imposed work of breathing in neonates. \u2022 Neopuff\u2019s T-piece caused vortices during exhalation. \u2022 CFD modeling proved effective for optimizing neonatal CPAP…
L\u00e4s mer<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-175","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/pages\/175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neores.se\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=175"}],"version-history":[{"count":60,"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/pages\/175\/revisions"}],"predecessor-version":[{"id":2588,"href":"https:\/\/neores.se\/index.php?rest_route=\/wp\/v2\/pages\/175\/revisions\/2588"}],"wp:attachment":[{"href":"https:\/\/neores.se\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}