Helping infants to breathe
The aim of the research group is to reduce the number of newborns needing ventilator care through optimisation and developing new strategies for assisting them in breathing on their own. The research is focused on resuscitation and respiratory support of infants in low-, middle- and high-income countries. It has several completed PhD projects, and the work is supported by the Swedish government through regional councils and research grants.
The research group is not supported by Neores and only Thomas Drevhammar has a conflict of interest. Neores was started as an academic spin-off and most of the research is still conducted within the research group.
Link to research group
CORSAD trial
The original trial results were published in JAMA pediatrics by the academic reearchgroup in June 2021. This publication has then been followed by two secondary analysis.
The research group has conducted a large multicenter study has been conducted at 7 different neonatal units in five European countries. Mothers at risk of delivery before week 28 were screened and 250 infants were randomized to standard treatment or treatment with rPAP. Of the 246 babies born alive, the mean gestational age was 26 weeks and more than 80% required immediate ventilation. In the delivery room, 55 children treated according to standard care were intubated, while 44 in the rPAP group. The lower delivery room intubation rate with rPAP was statistically significant. Two secondary analyses have been published after the original publication. Neores was not involved in the trial. Thomas Drevhammar is a co-authour with a declared conflict of interest.
